Soluble Dietary Fibres in the Prevention of Type 2 Diabetes Mellitus

Not Applicable

Completed

• Conditions: Type 2 Diabetes Mellitus; Obesity
• Interventions: Other: Polydextrose and soluble gluco fibre

• Registration Number: NCT01163006
• Lead Sponsor: Maastricht University Medical Center

Brief Summary

Controlling the glycemic impact of foodstuffs (by reducing the glycemic load of the diet by using soluble dietary fibres) may reduce the glycemic or insulinemic response. This may in turn result in a reduced inhibition of postprandial fat oxidation rate and a lower plasma triacylglycerol concentration A higher postprandial fat oxidation may result in less lipid accumulation in non-adipose tissue thereby improving insulin sensitivity and the metabolic profile in the longer term.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-03
• Status Verified: 2010-07
• Study First Submitted: 2010-07-14
• Study First Submitted QC: 2010-07-14
• Study First Posted: 2010-07-15
• Primary Completion: 2011-03
• Study Completion: 2011-03
• Last Update Submitted: 2018-01-05
• Last Update Posted: 2018-01-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Overweight men and women

Exclusion Criteria

• regular smokers, athletes, diabetes mellitus

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
soluble glucofibre	Polydextrose and soluble gluco fibre	-
polydextrose	Polydextrose and soluble gluco fibre	-
isocaloric dietary control	Polydextrose and soluble gluco fibre	-
full caloric control	Polydextrose and soluble gluco fibre	-

Primary Outcome Measures

Name	Time	Method
fat oxidation

Secondary Outcome Measures

Name	Time	Method
24h glucose pattern

Trial Locations

Locations (1)

Maastricht University; 🇳🇱 Maastricht, Netherlands