Correlation Between Altered Glycometabolic Status and Joint Inflammation in Diabetic Patients With Osteoarthritis Undergoing Knee Arthroplasty
Recruiting
- Conditions
- To Evaluate a Linear Positive Correlation Between Plasma HbA1c and Synovial IL-6 in Diabetic Patients
- Registration Number
- NCT05150119
- Lead Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
- Brief Summary
Evaluate the correlation between altered glycometabolic status and joint inflammation in diabetic patients with osteoarthritis undergoing knee replacement surgery
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
- Diabetic patients
- Patients with osteoarthritis awaiting knee replacement surgery
- Patients awaiting knee replacement surgery
- Patients who agree to sign informed consent
Exclusion Criteria
- Patients less than 55 years of age.
- Patients over 85 years of age.
- Patients who are unable to understand and want.
- Patients with severe neurological disorders or with severe disabilities.
- Rheumatoid arthritis patients
- Cancer patients
- Patients suffering from chronic inflammatory bowel syndromes (RCU and Crohn's disease)
- Patients on immunosuppressive therapy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate if there is a linear positive correlation between plasma glycated hemoglobin concentration HbA1c and synovial IL-6 in diabetic patient 2 day To evaluate if there is a linear positive correlation between plasma glycated hemoglobin concentration HbA1c and synovial IL-6 in diabetic patient
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
IRCCS Istituto Ortopedico Galeazzi
🇮🇹Milan, Italy