NL-OMON41647已完成3 期
Early Beta blocker Administration before reperfusion in patients with ST-Elevation Myocardial Infarction who are planned to undergo primary PCI - Early-ßAMI
Maatschap cardiologie Isala0 个研究点目标入组 450 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 450
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Patients >= 18 years of age with symptoms of acute ST-elevation myocardial infarction of more than 30 min but less than 12 hours and on the ECG ST-segment elevation of >=0.1 mV in two adjacent limb electrocardiograph (ECG) leads and >=0.2 mV in two adjacent precordial ECG leads or new left bundle branch block (LBBB).
- •Verbal followed by written informed consents.
- •PCI-center located within 90 minutes
排除标准
- •Severe Hypotension (systolic blood pressure < 100 mmHg)
- •Cardiogenic shock (severe dyspnoea, hypotension and oxygen saturation <92%, systolic blood pressure < 100 mmHg and heartrate > 110/min)
- •Known with asthma
- •Severe bradycardia at sinusrythm (< 60 bpm)
- •PR interval >240 ms or second- and/or third degree atrio-ventricular (AV) block
- •History of previous myocardial infarction
- •Killip class III-IV
- •Pacemaker/implantable cardioverter defibrillator (ICD)
- •Unable to provide informed consent
- •Patient is pregnant or breastfeeding
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