TCTR20201203005
Not yet recruiting
Phase 2
Comparing the perioperative blood loss in hypovolemic phlebotomy vs non-hypovolemic phlebotomy with low central venous pressure in patients undergoing open liver resection, A Prospective Randomized Double-Blind Controlled Study
none0 sites100 target enrollmentDecember 3, 2020
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- The role of hypovolemic phlebotomy to maintained low CVP and minimized blood loss and blood transfusion during open liver resection.
- Sponsor
- none
- Enrollment
- 100
- Status
- Not yet recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. All genders, age 18 to 70 years old
- •2\. American Society of Anesthesiologists (ASA) physical status classification of I\-III
- •3\. The patients who scheduled in elective open liver resection and diagnosed Hepatocellular Carcinoma, Cholangiocarcinoma, Liver metastasis, and Benign malignant tumor.
Exclusion Criteria
- •1\. Pregnancy
- •2\. Refusal of blood and blood products transfusion
- •3\. Anemia (Hb \<10 g/dL)
- •4\. Active cardiac conditions (unstable coronary syndromes, decompensated heart failure, significant arrhythmias, severe valvular disease, active coronary artery disease within 6 months prior surgery)
- •5\. History of significant cerebrovascular disease (Patients with clinically significant stroke/CVA within 6 months prior surgery, severe carotid stenosis)
- •6\. History of significant peripheral vascular disease (Patients with regular claudication)
- •7\. History of congestive heart failure (CHF)
- •8\. Restrictive or obstructive pulmonary disease (COPD)
- •9\. Renal dysfunction (creatinine \> 1\.8 mg/dL)
- •10\. Abnormal coagulation parameters (INR \>1\.5 not on warfarin and/or platelet count \<100,000\)
Outcomes
Primary Outcomes
Not specified
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