Efficacy of intravenous vs intraperitoneal lidocaine for postoperative analgesia in laparoscopic cholecystectomy: a randomized, double-blind, placebo-controlled trial

Phase 1

Completed

• Conditions: Total opioid consumption in patients receiving lidocaine IV or IP vs saline in laparoschopic surgeryIncidence of shoulder painTime discharge criteria met; at 6, 12 hours, or 24 hours after sur; Cholecystectomy, Laparoscopic, Lidocaine, Analgesics, Ambulatory surgery

• Registration Number: TCTR20190316001
• Lead Sponsor: Chiang Mai University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-03-16
• Study Completion: 2020-06-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 162

Inclusion Criteria

All genders between 18 to 70 years of age with good conscious
- Patients with American Society of Anesthesiologists (ASA) physical status classification of I-II
- Patients subjected to elective laparoscopic cholecystectomy
- Patients who have given informed consent to participate in this study

Exclusion Criteria

- Patients with BMI >35 (morbid obesity)
- Patients with suspected CA gallbladder and acute cholecystitis
-Patients with severe obstructive sleep apnea
-Patients with preexisting chronic pain, including those who are currently receiving opioid treatments, and those who received analgesics 24 hours prior to surgery
- Patients with a history of local anesthetic allergy
-Patients with previous abdominal surgeries
- Patients with severe liver, cardiac or renal disease (serum creatinine >2 mg/dl)
-Patients who are unable to communicate and cooperate to pain assessment

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Opioid consumption 0, 2, 4, 6, 12, 24 hours Visual analogue scale

Secondary Outcome Measures

Name	Time	Method
Recovery time at 24 hours Discharge criteria,Side effects Through out Signs and symptoms