Iatrogenic Effects of Treatment for Childhood Cancer Constitution of a Biological Samples Bank
- Conditions
- Paediatric Malignancies
- Interventions
- Procedure: saliva samplesProcedure: blood samples
- Registration Number
- NCT02666625
- Lead Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
- Brief Summary
The constitution of a biological samples bank, attached to epidemiological studies Cohort F-CCSS on iatrogenic effects of treatment of childhood cancer, will identify genetic variants that can modulate the iatrogenic risks of these treatments. The main objective is to provide a biological samples bank to consider, besides the carcinogenic risks, the risk of other iatrogenic diseases in these children, in particular cardiac, cerebrovascular, lung, bone and kidney. These conditions can be very incapacitating and in some cases, fatal. Their impact, however, is poorly estimated as occurring in adulthood, they are rarely made in relation to the treatment received in childhood. The overall project is expected to eventually better define the iatrogenic effects prevention strategies for cancer treatment.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 6000
- Patients treated for a first cancer in childhood
- Adult patients
- Signed informed consent
- Patient insured or enjoying a social security scheme
- Minor patients
- Under legal protection measure patients
- Refusal of consent
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Patients treated for cancer in childhood blood samples - Patients treated for cancer in childhood saliva samples -
- Primary Outcome Measures
Name Time Method Study of genetic factors who might lead to secondary iatrogenic pathology due to treatment of a childhood cancer seven years
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Gustave Roussy Cancer Campus Grand Paris
🇫🇷Villejuif, Val de Marne, France