To compare the effect of esmolol v/s dexmedetomidine on blood pressure and heart rate during and after laryngoscopy and endotracheal intubation in patients undergoing elective laprascopic gynecological surgeries.
Not yet recruiting
- Conditions
- Inflammatory disease of cervix uteri, (2) ICD-10 Condition: R098||Other specified symptoms and signsinvolving the circulatory and respiratory systems,
- Registration Number
- CTRI/2022/10/046140
- Lead Sponsor
- Department of anaesthesiology Sawai mansingh medical college and attached hospitals
- Brief Summary
The purpose of your study is to compare the effects of esmolol and dexmedetomidine on heart rate and blood pressure in response to laryngoscopy and endotracheal intubation and to find out which drug is more effective.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
- 1.ASA grade 1-2.
- 2.patients body weight 40-70 kgs.
- 3.undergoing laparoscopic gyencological surgery.
Exclusion Criteria
- 1.patients not willing to give consent.
- 2.patients with anticipated difficult airway and laryngoscopy time more than 20 seconds.
- Chronic disease -hypertension , diabetes,hepatic disease.
- 4.patients on beta blockers.
- 5.pregnant and lactating women.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine the difference in change in hemodynamic response from baseline after administrating esmolol and dexmedetomidine during laryngoscopy and endotracheal intubation At 1 min 3 min 5 min 7 min 10 min and at 20 min
- Secondary Outcome Measures
Name Time Method To determine proportion of cases who developed the side effects after administrating drug 1,3,5,7,10,30min
Trial Locations
- Locations (1)
SMS medical college
🇮🇳Jaipur, RAJASTHAN, India
SMS medical college🇮🇳Jaipur, RAJASTHAN, IndiaDr chandrasekhar ChatterjeePrincipal investigator9828088092chatterjee.chandrashekhar@gmail.com