A prospective study for impact of the carotid artery stenting on cognitive function in patients with extracranial carotid artery stenosis.
Not Applicable
- Conditions
- Extracranial carotid artery stenosis
- Registration Number
- JPRN-UMIN000020045
- Lead Sponsor
- Osaka General Medical Center
- Brief Summary
Post-CAS cognitive function varied between patients and between categories of neuropsychological tests. Although there was no significant overall improvement in working memory scores after CAS, post-CAS working memory scores changed in negative correlation with changes in FC of the DMN between the precentral/superior frontal gyrus and middle frontal gyrus. In addition, FC of the DMN between the preoperative precentral/superior frontal gyrus and medial frontal gyrus correlated positively with the post-CAS improvement in working memory.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
1)Patients judged not to be eligible by the primary doctor 2)Any other disease which can affect patient's cognitive function
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement of cognitive function after carotid artery stenting
- Secondary Outcome Measures
Name Time Method 1)Alteration of functional connectivity 2)Alteration of regional cerebral blood flow