High Intensity Laser and Exercises in Knee OA
- Conditions
- Chronic Knee Osteoarthritis
- Interventions
- Device: High Intensity Laser Therapy
- Registration Number
- NCT04751253
- Lead Sponsor
- Cairo University
- Brief Summary
The purpose of the study is to compare the effect of different doses of energies of high-intensity LASER on pain and functional activity in patients with chronic knee OA.
- Detailed Description
Adding HILT to the traditional physical therapy program may reduce pain and improve the functional status of the affected joints. This may provide clinicians with an understanding of the different treatment modalities that may improve the quality of life of patients suffering from chronic knee OA. Which may benefit a wide range of individuals affected by this chronic and widespread disease all over the world.
Although little is known about the efficacy or mechanism of action of what has been termed ''high-intensity laser therapy'' using Nd: YAG lasers it has become commercially available in veterinary practice and is being marketed for the treatment of musculoskeletal disease. clinical research specific to Nd: YAG high-intensity laser therapy is required, as it is being used with little supporting evidence.
As there was no evidence about the best protocol for the treatment of knee OA as each study was using different doses, different sites of application, different number of phases, frequency of sessions, and the interval between sessions that make it difficult to have the best results. Specifically, the dosage range in literature was ranged from 1250 to 3000 J as total energy transmitted during one treatment session. The current study is an attempt to answer the question of which dosage of the energy of high-intensity LASER is more effective on pain and functional activities in patients with chronic knee OA at the third degree of osteoarthritis as determined by (Kellgren/Lawrence grading system) as it was recommended that LASER is an ideal treatment for subjects in the later stages of OA .
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 51
- All subjects diagnosed as third degree chronic knee OA as determined by (Kellgren/Lawrence grading system) (Kellgren and Lawrence, 1957).
- Aged between 50- 70 years
- Persistent pain ≥4 on the visual analog scale (VAS) for more than 3 months in one or both knees.
- Body mass index (BMI) ≤30 kg/m2.
- Self-reported disability due to knee pain with a score of at least 25 on the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC).
- All subjects who will participate in this study will read, sign and date an informed consent form which required by ethical committee of faculty of physical therapy, Cairo university
Patients will be excluded if they have the following conditions:
- History of joint replacement.
- Symptoms or signs suggestive of another cause of knee pain.
- Rheumatoid arthritis.
- Steroid injection or knee surgery (previous six months).
- acute inflammation around knee joint.
- Underlying disease such as malignancy.
- Infection or systemic disease of musculoskeletal system
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- FACTORIAL
- Arm && Interventions
Group Intervention Description 3000 J + exercises High Intensity Laser Therapy consist of 17 patients, they will receive the application of HILT with intensity 3000 J plus exercises. 1500 J + exercises High Intensity Laser Therapy consist of 17 patients, they will receive the application of HILT with intensity 1500 J plus exercises. exercises + sham LASER High Intensity Laser Therapy consist of 17 patients, they will apply exercises plus sham LASER.
- Primary Outcome Measures
Name Time Method visual analogue scale 8 weeks pain intensity
The functional disability assessment 8 weeks The Western Ontario and McMaster Universities Osteoarthritis Index
- Secondary Outcome Measures
Name Time Method