Effects of One-handed and Two-handed Mask Ventilation Techniques on Global and Regional Lung Ventilation

Not Applicable

• Conditions: Anesthesia
• Interventions: Other: Two-handed mask ventilation; Other: One-handed mask ventilation

• Registration Number: NCT04617665
• Lead Sponsor: Fudan University

Brief Summary

Two-handed mask ventilation has been shown to provide higher tidal volume than one-handed mask ventilation. The effects of the two techniques on respiratory mechanics during induction of general anesthesia, however, still need to be determined.

Detailed Description

Mask positive pressure ventilation always causes the changes of respiratory mechanics such as ventral redistribution of regional ventilation, which impairs gas exchange. Two-handed mask ventilation has been shown to improve gas exchange by providing higher tidal volume than one-handed mask ventilation. We hypothesis that those higher tidal volume caused by two-handed mask ventilation would also improve the respiratory mechanics during induction of general anesthesia.

Study Timeline

• Status Verified: 2020-10
• Study First Submitted: 2020-10-25
• Study Start: 2020-11
• Study First Submitted QC: 2020-11-04
• Last Update Submitted: 2020-11-04
• Study First Posted: 2020-11-05
• Last Update Posted: 2020-11-05
• Primary Completion: 2020-12
• Study Completion: 2020-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Scheduled for elective surgery with general anesthesia
• American Society of Anesthesiologist (ASA) physical class of I-II.

Read More

Exclusion Criteria

• acute and chronic respiratory disorders, including chronic obstructive
• pulmonary disease (COPD) and asthma;
• a history of lung surgery;
• exist risk of reflux and aspiration;
• patients requiring an awake intubation;
• facial and thoracic deformities;
• implants exist in the body, such as cardiac pacemakers;
• pregnant women.

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Two-handed mask ventilation	Two-handed mask ventilation	For the two-handed mask ventilation, the provider's thumb and thenar eminence of each hand are held parallel, adjacent to the mask connector, and depress each side of the mask. The second through fifth digits wrap around and elevate the mandible to draw it anteriorly into the mask establishing both a jaw-thrust and chin-lift maneuver when appropriate.
One-handed mask ventilation	One-handed mask ventilation	For the one-handed mask ventilation, only one hand can be used to achieve the face mask seal. The left thumb and index finger form a ''C,'' providing anterior pressure over the mask, while the third, fourth, and fifth fingers form an ''E'' to lift the jaw.

Primary Outcome Measures

Name	Time	Method
global inhomogeneity (GI)	8 weeks	EIT images will be acquired by using the EIT monitor (Drager Medical Gmbh, Lubeck, Germany). And a software package (Electrical impedance tomography diag custom software provided by Drager Medical) will be used to quantitatively analyze the EIT data. 0% = homogenous

Secondary Outcome Measures

Name	Time	Method
PaO2/FiO2	8 weeks	PaO2/FiO2 will be recorded through arterial blood gas analysis.
regional ventilation delay (RVD)	8 weeks	EIT images will be acquired by using the EIT monitor (Drager Medical Gmbh, Lubeck, Germany). And a software package (Electrical impedance tomography diag custom software provided by Drager Medical) will be used to quantitatively analyze the EIT data.
Expiratory tidal volume (TV)	8 weeks	Expiratory tidal volume will be recorded through the anesthesia machine.
centre of ventilation (CoV)	8 weeks	EIT images will be acquired by using the EIT monitor (Drager Medical Gmbh, Lubeck, Germany). And a software package (Electrical impedance tomography diag custom software provided by Drager Medical) will be used to quantitatively analyze the EIT data. 100% = entirely dorsal.
ventilation of regional lung ( %)	8 weeks	EIT images will be acquired by using the EIT monitor (Drager Medical Gmbh, Lubeck, Germany). And a software package (Electrical impedance tomography diag custom software provided by Drager Medical) will be used to quantitatively analyze the EIT data.