A study of whether pediatric sedation calms down when lidocaine and esmolol are given to the child at the end of the surgery
Not Applicable
Completed
- Conditions
- Not Applicable
- Registration Number
- KCT0002925
- Lead Sponsor
- Soon Chun Hyang University Hospital Cheonan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 84
Inclusion Criteria
Eighty-four healthy children aged 3-9 years and of American Society of Anesthesiologist (ASA) physical status I and II
Exclusion Criteria
Patients with cardiac disorders, respiratory diseases, or mental disorders were excluded from the study.
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method objective pain score (OPS);the Cole 5-point score (CPS),;the Richmond-agitation-sedation-scale (RASS)
- Secondary Outcome Measures
Name Time Method Age(y);Weight(kg);Sex(M/F);Operation duration(min);Anesthesia duration(min);Extubation time(min);Recovery time(min);Fentanyl dose;Blood pressure;Heart rate;Oxygen saturation
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What are the molecular mechanisms by which esmolol and lidocaine reduce postoperative agitation in pediatric patients?
How does the combination of esmolol and lidocaine compare to standard-of-care sedatives in managing pediatric emergence agitation?
Are there specific biomarkers that predict response to esmolol and lidocaine in pediatric anesthesia recovery?
What are the potential adverse events associated with esmolol and lidocaine use in pediatric sedation and how are they managed?
What other adrenergic antagonists or local anesthetics are being studied for postoperative agitation in pediatric patients?