Observational Study on Costs and Caregiver Burden in Alzheimer's Disease

AstraZeneca1 site in 1 country2,400 target enrollmentJune 2007

ConditionsAlzheimer's Disease

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Alzheimer's Disease
Sponsor: AstraZeneca
Enrollment: 2400
Locations: 1
Primary Endpoint: Mini-Mental State Examination (MMSE), Disability Assessment for Dementia Scale (DAD), Neuropsychiatric Inventory Questionnaire (NPI-Q)
Status: Completed
Last Updated: 17 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Objective of study is to assess the costs of care, objective and subjective caregiver burden and quality of life in relation to disease severity measured by cognitive function, ADL capabilities and presence of behavioral disturbances in Alzheimer's disease

Registry

clinicaltrials.gov

Start Date

June 2007

End Date

January 2009

Last Updated

17 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

AstraZeneca

Eligibility Criteria

Inclusion Criteria

•Clinical diagnosis of possible or probable Alzheimer's disease, with or without vascular elements
•The primary caregiver can be identified
•The patient and his/her primary caregiver are both willing and able to participate in the study

Exclusion Criteria

•Patient or caregiver affected by alcohol or narcotics to the extent that it interferes with the completion of the study
•Patient or caregiver does not understand English
•Patient and/ or caregiver is the physician or physician's staff
•Patient and/ or caregiver is a family member of the physician or physician's staff

Outcomes

Primary Outcomes

Mini-Mental State Examination (MMSE), Disability Assessment for Dementia Scale (DAD), Neuropsychiatric Inventory Questionnaire (NPI-Q)

Time Frame: Collected one time only

Secondary Outcomes

Resource Utilization in Dementia (RUD)(collected one time only)
Short Form - 12 domains instrument (SF-12)(collected one time only)
World Health Organization Quality of Life instrument (WHO-QoL)(collected one time only)
Zarit Caregiver Burden Interview (ZBI)(collected one time only)
15 domains Quality of Life Index instrument (15D)(collected one time only)