Observational Study on Costs and Caregiver Burden in Alzheimer's Disease
Completed
- Conditions
- Alzheimer's Disease
- Registration Number
- NCT00698165
- Lead Sponsor
- AstraZeneca
- Brief Summary
Objective of study is to assess the costs of care, objective and subjective caregiver burden and quality of life in relation to disease severity measured by cognitive function, ADL capabilities and presence of behavioral disturbances in Alzheimer's disease
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 2400
Inclusion Criteria
- Clinical diagnosis of possible or probable Alzheimer's disease, with or without vascular elements
- The primary caregiver can be identified
- The patient and his/her primary caregiver are both willing and able to participate in the study
Exclusion Criteria
- Patient or caregiver affected by alcohol or narcotics to the extent that it interferes with the completion of the study
- Patient or caregiver does not understand English
- Patient and/ or caregiver is the physician or physician's staff
- Patient and/ or caregiver is a family member of the physician or physician's staff
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mini-Mental State Examination (MMSE), Disability Assessment for Dementia Scale (DAD), Neuropsychiatric Inventory Questionnaire (NPI-Q) Collected one time only
- Secondary Outcome Measures
Name Time Method Resource Utilization in Dementia (RUD) collected one time only Short Form - 12 domains instrument (SF-12) collected one time only World Health Organization Quality of Life instrument (WHO-QoL) collected one time only Zarit Caregiver Burden Interview (ZBI) collected one time only 15 domains Quality of Life Index instrument (15D) collected one time only
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie caregiver burden progression in Alzheimer's disease as studied in NCT00698165?
How do costs of care in NCT00698165 compare to standard-of-care economic models for Alzheimer's management?
What biomarkers correlate with behavioral disturbances and disease severity in Alzheimer's observational studies like NCT00698165?
What adverse events are associated with Alzheimer's disease progression in AstraZeneca's observational study NCT00698165?
How do combination therapies targeting AChE and NMDA receptors compare to care strategies observed in NCT00698165 for Alzheimer's patients?
Trial Locations
- Locations (1)
Research Site
🇬🇧Uckfield, United Kingdom
Research Site🇬🇧Uckfield, United Kingdom