A 2hr Accelerated Diagnostic Protocol to Assess patients with chest Pain symptoms using contemporary Troponins as the only biomarker (ADAPT): a prospective observational validation study

Not Applicable

Recruiting

• Conditions: Chest pain of possible cardiac origin; Cardiovascular - Coronary heart disease

• Registration Number: ACTRN12611001069943
• Lead Sponsor: Christchurch Cardio-Endocrine Research Group

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-10-14
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 2000

Inclusion Criteria

Adults presenting to the trial hospital Emergency Department with chest pain of possible cardiac origin

Exclusion Criteria

Age < 18 years. Non-resident in country of recruitment. Patients for whom follow-up will not be possible either due to lack of onward contact address or because they will be overseas. Unable or unwilling to consent

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To prospectively validate an accelerated chest pain algorithm involving core lab Troponin I measurements over a 2 hour time period from presentation to the Emergency Department (ED) in patients with possible Acute Coronary Syndrome (ACS).<br>Occurence of patient outcomes at 30 days and 1 year post presentation will be determined using patient follow-up at 45 days, 6 months and 1 year post presentation.[30 days post-presentation]

Secondary Outcome Measures

Name	Time	Method
To determine the potential cost benefit for the health service of such a strategy in terms of case weight costing and bed days.[From presentation to the Emergency Department at trial hospital , then at 30 days and 1 year for all cause readmission(s) and/or death.]