Analgesic Efficacy of Ketoprofen Transdermal Patch Versus Ibuprofen Tablet on Post-Endodontic Pai

Phase 3

• Conditions: Irreversible pulpitis (dental).; Other diseases of pulp and periapical tissues; K04.99

• Registration Number: IRCT20190716044230N1
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 18 May 2020

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

Patients whom their physical status is classified as ASA I
Mandibular first/second molar diagnosed as irreversible pulpitis with moderate to severe pain
Positive response to electric pulp test, lingering pain to cold test which validate the diagnosis of irreversible pulpitis for each tooth

Exclusion Criteria

Having any systemic disorders, gastrointestinal disease or allergy which interfere with NSAIDS
Allergy to local anesthesia drugs or sulfite
Teeth that are not appropriate to be restorated or teeth with severe periodontal disease which are not suitable for endodontic treatment
Patients with swelling or fistula
Using any analgesic drug in the past 12 hours
Spontaneous pain which requires emergency treatment
Not being able to give informed consent or not being able to read and write
Pregnant or breastfeeding women
Exit criteria include disability (for any reason) in patient's fallow-up, inappropriate endodontic treatment or a two visit treatment and using other analgesics along with the study drugs.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain intensity after root canal treatment. Timepoint: Pain measurement immediately after root canal treatment and 2, 4, 8,12, 24 and 48 hours after treatment. Method of measurement: Numerical rating scale (NRS).