effect of giving magnesium sulphate before surgery on decreasing muscle contractions caused by succinylcholine, muscle pain after surgery and effect on serum pottasium
Phase 4
- Conditions
- Health Condition 1: R253- Fasciculation
- Registration Number
- CTRI/2024/08/072257
- Lead Sponsor
- Rajendra institute of medical sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
written and informed consent,
patients aged between 20 and 50 years posted for elective surgery under general anesthesia.
ASA (American society of anesthesiologists) grade I and grade II
pre-operative serum magnesium within normal limits
Exclusion Criteria
Consent refusal
ASA grade III and IV
Abnormal levels of serum magnesium and serum calcium
History of adverse drug reactions to relevant drugs
ASA grade III or above
contraindication to administration of relevant drugs
BMI more than 25 or less than 18
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method grade of fasciculations after administration of succinyl choline <br/ ><br>grade of post operative myalgia <br/ ><br>serum potassium levels following intubationTimepoint: post operative myalgia will be measured 24 hours after surgery <br/ ><br>serum potassium levels will be measured immediately after intubation
- Secondary Outcome Measures
Name Time Method hemodynamic response to intubationTimepoint: measured at one, three, five and ten minutes