Is early colonoscopy in patients with acute rectal blood loss better than standard colonoscopy?
Not Applicable
Completed
- Conditions
- GastroenterologyDigestive System
- Registration Number
- ISRCTN14530195
- Lead Sponsor
- Research Fund of the Haaglanden Medical Centre
- Brief Summary
1. 2018 results in https://www.ncbi.nlm.nih.gov/pubmed/29734211 (added 29/01/2019)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 132
Inclusion Criteria
1. Aged 18 years or over
2. Last bloody bowel movement within 24 hours of presentation
3. Ability to provide informed consent
4. No suspicion of or exclusion of an upper gastrointestinal bleeding source
Exclusion Criteria
1. Known or suspected acute ischemic bowel, perforation or peritonitis
2. Hemodynamic instability refractory to resuscitation
3. Coagulopathy refractory to correction
4. Documented pregnancy
5. Serious comorbidities that would preclude the use of colonoscopy in standard clinical practice (i.e. severe COPD, severe cardiovascular comorbidity)
6. Decreased level of consciousness.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hospital length of stay (in days) is measured calculated using the date and time of admission to hospital and the date and time of hospital discharge.
- Secondary Outcome Measures
Name Time Method <br> 1. The yield of colonoscopy, defined as diagnosing either a confirmed or presumptive source of bleeding and treatment if feasible is obtained from electronic patient charts (colonoscopy reports)<br> 2. The number of packed red blood cells is obtained from the electronic patient charts<br> 3. Information on readmissions and the reason for readmission (rectal blood loss) is obtained from the electronic patient chart<br> 4. Information on complications are obtained from the electronic patient chart<br> 5. 30 day mortality is obtained from the electronic patient chart<br>