To study the correlation of Corneal Parameters and visual acuity outcomes after Manual DSEK (Descemets stripping endothelial Keratoplasty ) in Pseudophakic Bullous Keratopathy .

Not yet recruiting

• Conditions: Bullous keratopathy, (2) ICD-10 Condition: O||Medical and Surgical, (3) ICD-10 Condition: H598||Other intraoperative and postprocedural complications and disorders of eye and adnexa, not elsewhere classified,

• Registration Number: CTRI/2021/10/037477
• Lead Sponsor: S N Medical CollegeAgra

Brief Summary

Descemet’s Stripping Endothelial Keratoplasty (DSEK) is a form of Lamellar Keratoplasty that allows selective replacement of diseased endothelium .According to literature , as Pseudophakic Bullous Keratopathy is the main cause of endothelial dysfunction in our country ,the advantages of  doing DSEK over PKP in these cases include rapid visual rehabilitation, minimal induced astigmatism,less chances of infection ,no suture related complications and negligible chances of catastrophic intraoperative complications such asexpulsive haemorrhage and choroidal detachment. DSEK lenticular can be prepared by Automated Keratome or Manually. At our centre, we don’t have Automated Keratome .So we will prepare the lenticule  manually.

This study aims at to correlate the Corneal Parameters and Visual acuity outcome after Manual DSEK in Pseudophakic Bullous Keratopathy.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-10-23
• Last Update Posted: 2022-06-26

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Patients of pseudophakic bullous keratopathy Ready to give consent and participate in study.

Exclusion Criteria

Other causes of Corneal edema Dense central corneal scarring uncontrolled Glaucoma PL absent.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Corneal Parameters and Visual acuity	F/U after surgery on day1 post op , day 7,day 15 post op then monthly till the completion of study

Secondary Outcome Measures

Name	Time	Method
intraoperative and post operative complication of Manual DSEK	F/U after surgery on day1 post op , day 7,day 15 post op then monthly till the completion of study

Trial Locations

Locations (1)

Department of Ophthalmology; 🇮🇳 Agra, UTTAR PRADESH, India

Department of Ophthalmology

🇮🇳Agra, UTTAR PRADESH, India

Dr Shefali Mazumdar

Principal investigator

9457288925

shefalimazumdar@gmail.com