antimicrobials in appendicitis

Recruiting

• Conditions: acute appendicitisoperative and non operative managementpossible microorganisms for acute appendicitis; Appendicitis; Perforated Appendicitis; simple, gangrenous, or perforated appendicitis; Microbial Sensitivity Tests

• Registration Number: TCTR20211222004
• Lead Sponsor: Faculty of Medicine for Girls (Cairo) Research Ethics Committee- RHBIRB2018122001

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-12-22
• Study Completion: 2022-04-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Prospectively One hundred patients undergoing open or laparoscopic appendectomy will be included in this study. Age more than one year is included Age from 1 year to 15 are defined as children
Diagnosis of Appendicitis will be confirmed either by operative finding, when there is doubt appendectomy specimen is sent for histopathological examination
A swab from the inflamed appendicular lumen, surrounding exudates or pus, or abscess cavity will be taken. The swab will be sent immediately for aerobic and anaerobic culture to detect any bacterial growth and to assess its antibiotic sensitivity.

Exclusion Criteria

Exclusion criteria
we will Exclude appendix found to be normal at appendicectomy, immunocompromised cases, associated chronic specific infection or Crohns, and suspected cases of malignancy

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Common bacteria associated with acute appendicitis take intraoperative swab and culture results will be read within few days culture positivity for responsible organism and its sensitivity for antibacterials

Secondary Outcome Measures

Name	Time	Method
accuracy of different methods in diagnosis of acute appeddicitis intraoperative intraoperative finding of acute appendicitis