MedPath

The new risk scoring system for predicting epithelial ovarian malignancy: Risk of ovarian cancer score (ROCS)

Recruiting
Conditions
Adnexal massOvarian cancer
Adnexal mass, Ovarian cancer, Predictive model, Risk scoring
Registration Number
TCTR20231103007
Lead Sponsor
Srinakharinwirot University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Male
Target Recruitment
124
Inclusion Criteria

Women with adnexal masses who undergone elective adnexal surgery at HRH Princess Maha Chakri Sirindhorn Medical Center
-Age more than 18 years old
-Basic information were completely recorded including age, menopausal status
-Preoperative ultrasound performed at at HRH Princess Maha Chakri Sirindhorn Medical Center, and performed by OB-GYN residents or OB-GYN fellow/ staffs, were completely recorded
-CA 125 level before operation
-Never have undergone uterus/ adnexal removal surgery
-If the pathology reported to be malignancy, only epithelial ovarian cancer cell type were included in this study

Exclusion Criteria

- Pregnancy
- previously diagnosed as ovarian cancer or any malignancy (any known cancer were excluded)
- no pathologic report of adnexal mass
- 10 predicting parameters were not all completely recorded

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
to create a new risk scoring system for predicting epithelial ovarian malignancy: Risk of ovarian cancer score (ROCS) after retrospective chart review all completed, then ROCS score can be generated via using stat Efficacy: sensitivity, specificity, PPV, NPV
Secondary Outcome Measures
NameTimeMethod
to compare the efficacy of ROCS in each subgroup 1. Borderline VS cancer/non-cancer 2. Borderline VS non-cancer 3. Borderline VS epithelial ovarian cancer 4. High grade cancer VS low grade cancer after ROCs score have been created, then subgroup analysis can be performed Efficacy: sensitivity, specificity, PPV, NPV
© Copyright 2025. All Rights Reserved by MedPath