Effects of ketone supplementation on rates of muscle protein synthesis following leg cycling in recreational active males

Dr Jamie Whitfield0 个研究点目标入组 10 人开始时间: 2023年2月21日最近更新: 2023年2月27日

试验速览

暂无简介。

•Participants will be recruited if they meet the following criteria:
•Aged 18-35 y
•BMI: 18.5-24.9 kg/m2
•Recreationally active (A-B grade cyclists or triathletes currently cycling ~200km/week) capable of completing the 180 min intermittent intensity exercise protocol
•No cardiopulmonary abnormalities
•No injuries
•Pass the ESSA pre-exercise screening tool and/or obtain GP clearance to exercise

•Known cardiovascular disease or diabetes mellitus
•Known bleeding disorder (i.e. hemophilia A [factor VIII deficiency]
•Hemophilia B [factor IX deficiency]
•von Willebrand disease, or other rare factor deficiencies including I, II, V, VII, X, XI, XII and XIII)
•Major or chronic illness that impairs mobility or eating/digestion
•Taking prescription medications (i.e. beta-blockers, anti-arrhythmic drugs, statins, insulin sensitising drugs, or drugs that increase the risk of bleeding [i.e. anticoagulants, antiplatelets, novel oral anticoagulants [NOAs], nonsteroidal anti-inflammatory drugs [NSAIDs], selective norepinephrine reuptake inhibitors [SNRI], or selective serotonin reuptake inhibitors [SSRIs]
•Unable or unwilling to have a muscle biopsy
•Weight has changed more than 5kg in past 3 months
•Currently on a restrictive diet
•Unable to attend the lab in Fitzroy, Melbourne for the 4 study visits for completion of study protocol

发起方

Dr Jamie Whitfield