NCT07532447已完成不适用
Metabolomic Characteristics of Patients With Non-small Cell Lung Cancer in Plasma, Tissue and Exhaled Breath Condensate: A Case-control Study
People's Hospital of Xinjiang Uygur Autonomous Region1 个研究点 分布在 1 个国家目标入组 74 人开始时间: 2022年4月30日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 74
- 试验地点
- 1
- 主要终点
- Untargeted metabolomics
研究概览
简要总结
Investigators collected tissue and plasma samples from patients with benign pulmonary nodules and non-small cell lung cancer (NSCLC). Exhaled breath condensate (EBC) samples were obtained from these patients using a breath condenser. Differential metabolites were identified in samples from 22 NSCLC patients and 20 benign controls using ultra-performance liquid chromatography-high resolution mass spectrometry-based untargeted metabolomics.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with non-small cell lung cancer or benign pulmonary nodules
排除标准
- •Metastatic lung cancer
研究组 & 干预措施
Non-small cell lung cancer - Preoperative peripheral blood group
Non-small cell lung cancer - Postoperative peripheral blood group
Benign pulmonary nodules - Peripheral blood group
Non-small cell lung cancer - exhaled breath condensate group
Benign pulmonary nodules - exhaled breath condensate group
Non-small cell lung cancer - adjacent tissue group
Non-small cell lung cancer - Cancer tissue group
结局指标
主要结局
Untargeted metabolomics
时间窗: 2022-2026
次要结局
未报告次要终点
研究者
研究点 (1)
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