Safety and Efficacy of High Flow Nasal Canula in Patients With Mild Hypercapnia

Mansoura University1 site in 1 country30 target enrollmentJanuary 1, 2023

ConditionsHypercapnia

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Hypercapnia
Sponsor: Mansoura University
Enrollment: 30
Locations: 1
Primary Endpoint: Arterial Blood Gases changes
Status: Completed
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Evaluate safety and efficacy of application ( high flow nasal canula) in cases with mild hypercapnia, included 30 patients who were hospitalized in Mansoura University chest department with mild Hypercapnia (Pco2 range 45-60 mmhg and power of hydrogen not less 7.30) of different pulmonary disease categories (Chronic obstructive pulmonary disease acute exacerbation, pneumonia, Interstitial lung diseases, etc).

Registry

clinicaltrials.gov

Start Date

January 1, 2023

End Date

July 1, 2023

Last Updated

2 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

Mansoura University

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•patients with mild Hypercapnia

Exclusion Criteria

•Excluded cases had age less than 18 years or pediatric group .
•patients with their mental state altered, confused, comatose, severe agitation or non cooperative
•Cases with moderate or severe Hypercapnia
•cases in need for immediate invasive mechanical ventilation
•cases with respiratory rate more than 35 breath per minute.
•cases with Respiratory exhaustion , fatigue , excess use of respiratory accessory muscles
•Shock , hemodynamic instability, post arrest cases,
•cases with facial trauma or severe nasal deformity,
•Patients with sleep breathing disorders or upper airway obstruction
•patients with history of home ventilation prior admission