Effectiveness of High-flow Nasal Cannula and Prone Positioning in Awake Patients With COVID-19 and Severe Acute Respiratory Failure
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Number of patients without intubation
研究概览
简要总结
The investigators evaluate the effects of High-flow nasal cannula (HFNC) in association with prone in patients with Covid-19 severe ARF.
详细描述
The investigators evaluate the effects of High-flow nasal cannula (HFNC) in association with prone in patients with Covid-19 severe ARF.
All patients with ARF related to Covid-19 and admitted to the ICU are turned in prone position whenever tolerated, while receiving oxygenation with HFNC.
Outcomes of interest are the rate of success or failure (defined as the need for intubation and mechanical ventilation)
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •aged ≥18 years, admitted to the medical ICU for confirmed Covid-19 and acute hypoxemic respiratory failure
排除标准
- •patients already intubated at admission or those requiring immediate intubation
结局指标
主要结局
Number of patients without intubation
时间窗: through study completion, an average of 28 days
successful oxygenation without intubation
次要结局
未报告次要终点
研究者
Fekri Abroug
Professor Head of the ICU
Hôpital Universitaire Fattouma Bourguiba