Effectiveness of High-flow Nasal Cannula and Prone Positioning in Awake Patients With COVID-19 and Severe Acute Respiratory Failure
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Hypoxemic Respiratory Failure
- Sponsor
- Hôpital Universitaire Fattouma Bourguiba
- Enrollment
- 120
- Locations
- 1
- Primary Endpoint
- Number of patients without intubation
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
The investigators evaluate the effects of High-flow nasal cannula (HFNC) in association with prone in patients with Covid-19 severe ARF.
Detailed Description
The investigators evaluate the effects of High-flow nasal cannula (HFNC) in association with prone in patients with Covid-19 severe ARF. All patients with ARF related to Covid-19 and admitted to the ICU are turned in prone position whenever tolerated, while receiving oxygenation with HFNC. Outcomes of interest are the rate of success or failure (defined as the need for intubation and mechanical ventilation)
Investigators
Fekri Abroug
Professor Head of the ICU
Hôpital Universitaire Fattouma Bourguiba
Eligibility Criteria
Inclusion Criteria
- •aged ≥18 years, admitted to the medical ICU for confirmed Covid-19 and acute hypoxemic respiratory failure
Exclusion Criteria
- •patients already intubated at admission or those requiring immediate intubation
Outcomes
Primary Outcomes
Number of patients without intubation
Time Frame: through study completion, an average of 28 days
successful oxygenation without intubation