QUARTZ LUNG: Quality of life after radiotherapy treatment for patients with stage IV non-small cell lung cancer

The Christie NHS Foundation Trust0 个研究点目标入组 448 人开始时间: 2024年8月19日最近更新: 2024年9月2日

适应症

试验速览

暂无简介。

•1. =16 years of age
•2. Stage IV NSCLC (radiological diagnosis confirmed at MDT as a minimum)
•3. Thoracic disease amenable to radiotherapy
•4. Provision of written informed consent
•5. For women of childbearing potential: a negative urine or serum pregnancy test within 7 days prior to the randomisation
•6. Patients not having systemic treatment
•7. ECOG Performance Status 0-3
•8. At least T2 and/or N1 disease
•9. Fit to receive low-dose palliative radiotherapy according to local guidelines and assessment

•1. The need for palliative radiotherapy to the thorax prior to randomisation
•2. Comorbidities which are considered a contraindication to radiotherapy by the treating clinical team, including interstitial lung disease and active connective tissue disorders
•3. History of prior malignant tumours likely to interfere with the protocol treatment or comparisons
•4. Leptomeningeal disease
•5. Women who are pregnant or breastfeeding
•6. Women of child-bearing potential who are not able or unwilling to use a highly effective method of contraception
•7. Patients who, in the judgment of the investigator, will be unlikely or unable to comply with the requirements of the protocol
•8. Patients receiving systemic therapy for NSCLC
•9. Prior treatments for this NSCLC
•10. Patients participating in a clinical trial of an investigational medicinal product

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