Prediction of Pain After Total Knee Arthroplasty

Completed

• Conditions: Knee Osteoarthritis

• Registration Number: NCT02254499
• Lead Sponsor: Rigshospitalet, Denmark

Brief Summary

Despite improvements in treatment, a significant part of patients have severe pain following knee arthroplasty. Preoperative identification of high-risk patients would allow for an intensive individualized analgesic treatment pre- and postoperatively and thus potentially in reduced pain acute and chronically.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-09
• Study First Submitted: 2014-09-29
• Study First Submitted QC: 2014-09-29
• Study First Posted: 2014-10-02
• Status Verified: 2015-09
• Primary Completion: 2015-09
• Study Completion: 2015-09
• Last Update Submitted: 2015-09-22
• Last Update Posted: 2015-09-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• primary unilateral TKA
• caucasian
• 50 - 80 years
• osteoarthritis

Exclusion Criteria

• deficient written or spoken danish
• impairment from psychological og neurological disease
• expected discharged to rehabilitation facility
• anticoagulant therapy
• allergies to analgesic treatment
• hypertension (systolic > 160 / diastolic > 100)
• ASA class ≥ 4

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain	24 hours postoperatively	Pain intensity on a NRS from 0 to 10 upon ambulation 24 hours following surgery

Secondary Outcome Measures

Name	Time	Method
Pain	From day 1 to day 14 following surgery	Daily diary reported pain intensity on a NRS (numeric rank scale) from 0 to 10 in average and when worse the first two weeks following knee arthroplasty.

Trial Locations

Locations (1)

Gentofte Hospital; 🇩🇰 Hellerup, Denmark