Continuous positive airway pressure in premature infants with respiratory distress syndrome
Not Applicable
- Conditions
- respiratory distress syndrome of preterm neonates.Respiratory distress syndrome of newborn
- Registration Number
- IRCT2014081918862N1
- Lead Sponsor
- Shahid Sadoughi University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Gestational age of 28-34 weeks; Birth weight 1000-2400 g; Respiratory distress syndrome; Respiratory score 5-7 under the Table Silverman Anderson
Exclusion criteria: Infants with congenital malformations including congenital heart disease, congenital diaphragmatic hernia, esophageal atresia, cleft lip and palate, Gastrochesia, emphalocele and gastrointestinal obstruction ; Moderate to severe asphyxia (II,III); Clinical signs of infection; Hematocrit less than 35; ICH , IVH (III.IV); Lack of parental consent
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Duration of CPAP. Timepoint: 12 to 24 hour and during daily visits. Method of measurement: PEEP Pressure , Fio2.;Duration of mechanical ventilation. Timepoint: 12 to 24 hour and during daily visits. Method of measurement: PIP , Fio2 , PEEP , RR.;Duration of Oxygen with Hood. Timepoint: 12 to 24 hour and during daily visits. Method of measurement: Fio2.
- Secondary Outcome Measures
Name Time Method Incidence of complications ( IVH,PDA,Pneumothorax). Timepoint: Daily until discharge. Method of measurement: IVH with brain sonography, PDA with echocardiography,Pneumothorax with CXR or transilumination.;Weight gain at discharge. Timepoint: Daily until discharge. Method of measurement: scale.;Duration of Hospitalization. Timepoint: Daily until discharge. Method of measurement: date.;Death. Timepoint: Daily until discharge. Method of measurement: Physical exam.