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IV Paracetamol Versus IV Dexketoprofen in Dysmenorrhea

Phase 4
Conditions
Dysmenorrhea
Interventions
Registration Number
NCT02373514
Lead Sponsor
Akdeniz University
Brief Summary

Patients presented with dysmenorrhea composed the study population. One gram paracetamol and 50 mg dexketoprofen in 100 ml saline with a rapid infusion were compared in ceasing dysmenorrhea in emergency department.

Detailed Description

Patients over 18 years old who presented with dysmenorrhea composed the study population. Patients received pain killer within the last six hours, physical findings consistent with peritoneal irritation, allergy to the study drugs, renal or liver failure, drug addiction, pregnancy or woman with lactation and denied to give inform consent were the exclusion criteria. The pain of the study patients are measured with visual analogue scale at baseline, 15th and 30th minutes. At the end of the 30 minutes, rescue drug need is also recorded.

Recruitment & Eligibility

Status
UNKNOWN
Sex
Female
Target Recruitment
100
Inclusion Criteria
  • Patients with dysmenorrhea
  • Patients over 18 years old
Exclusion Criteria
  • denied to give inform consent
  • Renal or liver failure
  • Allergy to the study drugs
  • Receiving pain killer within the last 6 hours.
  • Physical examination findings consistent with peritoneal irritation
  • Pregnancy or patients with lactation
  • Drug addiction

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
DexketoprofenDexketoprofenIntravenous 50 mg dexketoprofen in 100 ml saline with rapid infusion
ParacetamolParacetamolIntravenous 1 gm paracetamol in 100 ml saline with rapid infusion
Primary Outcome Measures
NameTimeMethod
Visual Analogue Scale30 minutes

Change in visual analogue scale at 30th minutes from baseline

Secondary Outcome Measures
NameTimeMethod
Rescue drug need30 minutes
Adverse effects30 minutes

Trial Locations

Locations (1)

Pamukkale University

🇹🇷

Denizli, Turkey

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