Compare the effect of two drugs, paracetamol and dexmedetomidine, on perioperative vitals & postoperative pain in patients undergoing laparoscopic cholecystectomy under general anaesthesia
Not Applicable
- Conditions
- Health Condition 1: K801- Calculus of gallbladder with othercholecystitis
- Registration Number
- CTRI/2024/05/066957
- Lead Sponsor
- Pt B D Sharma PGIMS Rohtak
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
The study will include 90 patients of either sex.
age 18–60 years, belonging to American Society of
Anesthesiologists (ASA) physical status of I-II with
scheduled for elective laparoscopic cholecystectomy
under general anaesthesia and will be assigned to
two groups
Exclusion Criteria
Obesity
Already receiving beta blocker or alpha-2 agonists
History of allergy to test drug
History of hypertension with or without medication
History of cardiopulmonary disease
History of hepatic and renal dysfunction
History of psychological disorders
History of alcohol and drug abuse
Receiving opioid analgesics during last 24 hours
before surgery
Heart Rate less than 50bpm
Refusal to participate in the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study the effectiveness of paracetamol & dexmedetomidine on peri-operative <br/ ><br>hemodynamics and postoperative analgesia in patients undergoing laparoscopic <br/ ><br>cholecystectomy under general anaesthesia .Timepoint: First of all, spo2, NIBP, and pulse rate will be recorded at baseline before and after the administration of drugs and pain score will be assessed at 1/2, 2, 4, and 6 hours in patients undergoing laparoscopic cholecystectomy under general anaesthesia .
- Secondary Outcome Measures
Name Time Method All the vital parameters (spo2, pulse rate, NIBP, & pain score) will be assessed.Timepoint: At baseline, just before & after the administration of drugs & pain score at 1/2, 2, 4 & 6 hours post-operatively