NCT01944878已完成不适用
Retrospective Observational Study of Impact of Portal Hypertension for the Peptic Ulcer in Liver Cirrhosis and Chronic Hepatitis
Chuncheon Sacred Heart Hospital1 个研究点 分布在 1 个国家目标入组 455 人开始时间: 2013年5月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 455
- 试验地点
- 1
- 主要终点
- The Association of HVPG and PUD in Patients With Liver Cirrhosis
研究概览
简要总结
The aim of this study is to assess the role of portal hypertension of peptic ulcer disease in liver cirrhosis and chronic hepatitis.
详细描述
Retrospective case-control study
- Investigators will analyze the medical records of hepatic vein pressure gradient (HVPG) and esophagogastroduodenoscopy (EGD) cases who had liver cirrhosis (LC) or chronic hepatitis in a single tertiary hospital (Chuncheon Sacred Heart hospital, Korea) within 2008~2012.
- Portal hypertension is assessed using HVPG measurement via transjugular approach.
- Peptic ulcer is evaluated through EGD within 3 months of HVPG measurement
- The association of Peptic ulcer with LC, chronic hepatitis and total population (LC or chronic hepatitis) will be assessed by univariate and multivariate analysis
- There is no specific time frame, because this study is retrospective observational study, however EGD data is enrolled if it was done within 3 month from HVPG measurement.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The patients who underwent hepatic vein pressure gradient (HVPG) measurement and esophagogastroduodenoscopy (EGD) and also had LC or chronic hepatitis
排除标准
- •The patients who have missing or incomplete HVPG or EGD data
- •The patients who underwent gastrectomy
- •The patients who have systemic malignancy
结局指标
主要结局
The Association of HVPG and PUD in Patients With Liver Cirrhosis
时间窗: Retrospective case-control study (from 2009 to 2012, up to 3 years)
The association of hepatic vein pressure gradient that reflects portal hypertension and peptic ulcer disease in patients with liver cirrhosis was assessed statistically. (NO specific time frame, only confined to 2009 to 2012, when the HVPG measurement was done). The Mann-Whitney test was used to evaluate the association between PUD or not and HVPG degree, by SPSS software.
次要结局
- The Association Between PUD and HVPG in Patients With Chronic Hepatitis(Retrospective case-control study (from 2009 to 2012, up to 3 years))
研究者
Chang Seok Bang
Principal investigator
Chuncheon Sacred Heart Hospital
研究点 (1)
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