Application of Two Different Follow-up Methods for Neonatal Jaundice in the Prevention of Severe Hyperbilirubinemia
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Neonatal Jaundice
- Sponsor
- Guizhou Provincial People's Hospital
- Enrollment
- 1000
- Locations
- 3
- Primary Endpoint
- Newborn follow-up rate
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
The goal of this observational study is to compare the effectiveness and efficiency for precaution of severe hyperbilirubinemia in neonate by different follow-up methods of neonatal jaundice. There are two kinds of follow-up methods in the investigators clinical practice. The one is internet plus follow-up model, the other is conventional clinic follow-up method. Parents of the participant neonates can choose one by themselves. After parents of the participant signed informed consent, the investigators recorded several information including severe hyperbilirubinemia, length of phototherapy, follow-up times, et al. Then the investigators analysed these data in order to know what kind of follow-up method is better to prevent severe hyperbilirubinemia and more easy to be accepted.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Gestational age ≥ 28 weeks, corrected gestational age ≤ 44 weeks;
- •Presence of skin yellowing, percutaneous measurement of jaundice or serum bilirubin concentration less than the phototherapy warning value for the same gestational age and day age group;
- •The vital signs are stable and meet the discharge requirements;
- •Agree to participate in this project and sign an informed consent form;
- •Parents have a certain understanding ability to cooperate in this study;
Exclusion Criteria
- •Direct bilirubin ≥34mmol/L;
- •Increased hepatic enzyme level more than twice of normal value;
- •Those infants who have developed bilirubin encephalopathy or neurological damage due to other reasons before follow-up;
- •Unable to continue follow-up due to other diseases.
Outcomes
Primary Outcomes
Newborn follow-up rate
Time Frame: 10,01,2023 to 10,01,2024
Number of newborns who completed the follow-up program/total number of follow-up newborns
Incidence of severe hyperbilirubinemia
Time Frame: 10,01,2023 to 10,01,2024
The peak concentration of serum bilirubin is more than the exchange criteria of same gestational age and day age group
Secondary Outcomes
- Incidence rate of acute bilirubin encephalopathy(10,01,2023 to 10,01,2024)
- Follow-up satisfaction(10,01,2023 to 10,01,2024)
- Average economic cost of treatment(10,01,2023 to 10,01,2024)
- Mean bilirubin level at admission(10,01,2023 to 10,01,2024)