Application of Two Different Follow-up Methods for Neonatal Jaundice in the Prevention of Severe Hyperbilirubinemia
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,000
- 试验地点
- 3
- 主要终点
- Newborn follow-up rate
研究概览
简要总结
The goal of this observational study is to compare the effectiveness and efficiency for precaution of severe hyperbilirubinemia in neonate by different follow-up methods of neonatal jaundice. There are two kinds of follow-up methods in the investigators clinical practice. The one is internet plus follow-up model, the other is conventional clinic follow-up method. Parents of the participant neonates can choose one by themselves. After parents of the participant signed informed consent, the investigators recorded several information including severe hyperbilirubinemia, length of phototherapy, follow-up times, et al. Then the investigators analysed these data in order to know what kind of follow-up method is better to prevent severe hyperbilirubinemia and more easy to be accepted.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 0 Days 至 16 Weeks（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Gestational age ≥ 28 weeks, corrected gestational age ≤ 44 weeks;
- •Presence of skin yellowing, percutaneous measurement of jaundice or serum bilirubin concentration less than the phototherapy warning value for the same gestational age and day age group;
- •The vital signs are stable and meet the discharge requirements;
- •Agree to participate in this project and sign an informed consent form;
- •Parents have a certain understanding ability to cooperate in this study;
排除标准
- •Direct bilirubin ≥34mmol/L;
- •Increased hepatic enzyme level more than twice of normal value;
- •Those infants who have developed bilirubin encephalopathy or neurological damage due to other reasons before follow-up;
- •Unable to continue follow-up due to other diseases.
结局指标
主要结局
Newborn follow-up rate
时间窗: 10,01,2023 to 10,01,2024
Number of newborns who completed the follow-up program/total number of follow-up newborns
Incidence of severe hyperbilirubinemia
时间窗: 10,01,2023 to 10,01,2024
The peak concentration of serum bilirubin is more than the exchange criteria of same gestational age and day age group
次要结局
- Incidence rate of acute bilirubin encephalopathy(10,01,2023 to 10,01,2024)
- Follow-up satisfaction(10,01,2023 to 10,01,2024)
- Average economic cost of treatment(10,01,2023 to 10,01,2024)
- Mean bilirubin level at admission(10,01,2023 to 10,01,2024)