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A Comparative Study of Two Patterns of Controlled Ovarian Hyperstimulation in Mid Follicular Phase or Early Luteal Phase for Egg Donors

Not Applicable
Completed
Conditions
Stimulation in the Ovary
Interventions
Procedure: Early luteal phase
Procedure: Late follicular phase -COH-
Registration Number
NCT01385332
Lead Sponsor
Parc de Salut Mar
Brief Summary

The purpose of this study is to determine the efficacy and safety of two new patterns of controlled ovarian hyperstimulation (defined as total number of picked up eggs). This study will be performed in egg donors but these new patterns will be implemented in fertility preservation patients.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
10
Inclusion Criteria
  • premenopausal women 18-30 years old, with FSH levels < 10mIU
  • irregular menstrual cycle
  • BMI between 12-28
  • signed inform consent
Exclusion Criteria
  • Polycystic ovarian syndrome, gonadotropins allergy

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
Early luteal phase -COH-Early luteal phaseWe perform an standard antagonist protocol beginning the second day of the menstrual cycle compared with an antagonist protocol beginning in the early luteal phase.
Late folicular phase - COH -Late follicular phase -COH-We perform an standard antagonist protocol beginning the second day of the menstrual cycle compared with an antagonist protocol beginning in the late follicular phase.
Primary Outcome Measures
NameTimeMethod
Number of eggsParticipants will be followed after 1-3 hrs of follicular aspiration.

The results will be presented in one year, egg recipients will be followed until 12 weeks of pregnancy.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Servei de Ginecologia i Obstetricia, Hospital del Mar-Parc Salut Mar

🇪🇸

Barcelona, Spain

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