Effect of Whole-body Vibration on Insulin Resistance in Obese Postmenopausal Women.

Not Applicable

Completed

• Conditions: Insulin Resistance
• Interventions: Device: Total body vibration; Other: moderate restricted diet

• Registration Number: NCT05961020
• Lead Sponsor: October 6 University

Brief Summary

This study will be conducted to investigate the Effect of whole-body vibration on insulin resistance in obese postmenopausal women

Detailed Description

The prevalence of obesity has tripled over the past four decades, imposing an enormous burden on people's health.

Obesity is associated with premature mortality and is a serious public health threat that accounts for a large proportion of the worldwide non-communicable disease burden, including type 2 diabetes, cardiovascular disease, hypertension, and certain cancers.

reported that "Whole-body vibration (WBV) training has been established as a useful method to improve physical fitness in obese individuals. Vibration stimulus during half squatting might suggest a long-term effect of WBV on the endocrine system. Therefore, in this study, The aim to investigate the effect of whole-body vibration on insulin resistance in obese postmenopausal.

Study Timeline

• Study Start: 2022-11-05
• Primary Completion: 2023-01-03
• Study First Submitted: 2023-07-06
• Study Completion: 2023-07-08
• Study First Submitted QC: 2023-07-25
• Study First Posted: 2023-07-27
• Status Verified: 2024-05
• Last Update Submitted: 2024-05-15
• Last Update Posted: 2024-05-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 40

Inclusion Criteria

• All women were postmenopausal with no menses at least 1 year.
• Their ages were ranged from 50-60 years old.
• Their body mass index (BMI) > 30 kg/m2.
• They were not engaged in any other treatment program.

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Exclusion Criteria

• Women with body mass index (BMI) < 30 kg/m2.
• Any cardio-respiratory diseases.
• Diabetes mellitus.
• with malignancy.
• with severe hemorrhage, acute viral disease and mental disorders.
• Smokers.
• Women with life threatening disorders as renal failure

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
20 women treated by whole body vibration.	Total body vibration	-
20 women was treated by moderate restricted diet for 3 months.	moderate restricted diet	-

Primary Outcome Measures

Name	Time	Method
BMI	up to 3 months	Weight and height were measured to detect the BMI according to the following equation: BMI= weight/height² (Kg/m²)
Waist circumference	up to 3 months	A non-stretchable tape measurement was used to measure waist circumference for all women in both groups A and B: mid-way between upper border of the lateral iliac crest and the lower border of the lowest rib at the end of gentle expiration with arm relaxed at sides.
Skin fold thickness	up to 3 months	Skin fold caliper was used to measure skin fold thickness at abdominal region for all women in both groups A and B
The Homeostatic model assessment (The HOMA-IR).	up to 3 months	The Homeostatic model assessment (The HOMA-IR).; A sample of 5ml of venous blood sample was drawn from all women after 12 hours fasting for measurement of fasting blood glucose, fasting blood insulin and then detection of insulin resistance (by HOMA -IR) through the equation: HOMA-IR=(Glucose ×Insulin)/405 glucose in mass unit (mg/dl)

Trial Locations

Locations (1)

Kerolous Ishak Shehata kelini; 🇪🇬 Cairo, Egypt