Effect of Whole-body Vibration on Insulin Resistance in Obese Postmenopausal Women.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- BMI
研究概览
简要总结
This study will be conducted to investigate the Effect of whole-body vibration on insulin resistance in obese postmenopausal women
详细描述
The prevalence of obesity has tripled over the past four decades, imposing an enormous burden on people's health.
Obesity is associated with premature mortality and is a serious public health threat that accounts for a large proportion of the worldwide non-communicable disease burden, including type 2 diabetes, cardiovascular disease, hypertension, and certain cancers.
reported that "Whole-body vibration (WBV) training has been established as a useful method to improve physical fitness in obese individuals. Vibration stimulus during half squatting might suggest a long-term effect of WBV on the endocrine system. Therefore, in this study, The aim to investigate the effect of whole-body vibration on insulin resistance in obese postmenopausal.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 50 Years 至 60 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •All women were postmenopausal with no menses at least 1 year.
- •Their ages were ranged from 50-60 years old.
- •Their body mass index (BMI) > 30 kg/m
- •They were not engaged in any other treatment program.
排除标准
- •Women with body mass index (BMI) < 30 kg/m
- •Any cardio-respiratory diseases.
- •Diabetes mellitus.
- •with malignancy.
- •with severe hemorrhage, acute viral disease and mental disorders.
- •Women with life threatening disorders as renal failure
结局指标
主要结局
BMI
时间窗: up to 3 months
Weight and height were measured to detect the BMI according to the following equation: BMI= weight/height² (Kg/m²)
Waist circumference
时间窗: up to 3 months
A non-stretchable tape measurement was used to measure waist circumference for all women in both groups A and B: mid-way between upper border of the lateral iliac crest and the lower border of the lowest rib at the end of gentle expiration with arm relaxed at sides.
Skin fold thickness
时间窗: up to 3 months
Skin fold caliper was used to measure skin fold thickness at abdominal region for all women in both groups A and B
The Homeostatic model assessment (The HOMA-IR).
时间窗: up to 3 months
The Homeostatic model assessment (The HOMA-IR). A sample of 5ml of venous blood sample was drawn from all women after 12 hours fasting for measurement of fasting blood glucose, fasting blood insulin and then detection of insulin resistance (by HOMA -IR) through the equation: HOMA-IR=(Glucose ×Insulin)/405 glucose in mass unit (mg/dl)
次要结局
未报告次要终点
研究者
Kerolous Ishak Shehata
principle investigator
October 6 University