NCT02468401已完成不适用
The Efficacy of a New Protocol for Preventing Contrast Induced Nephropathy in Patients With Advanced Renal Dysfunction Undergoing Coronary Interventions
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Changes in glomerular filtration rate following coronary angiography or intervention
研究概览
简要总结
There is a pressing need to find effective strategies for the prevention of contrast induced nephropathy in patients with advanced renal dysfunction. The current study was designed to assess the efficacy of a new protocol for preventing contrast induced nephropathy in patients with advanced renal dysfunction undergoing coronary interventions
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with estimated glomerular filtration rate<45ml/min undergoing coronary angiography due to one of the following indications in accordance with the 2014 guidelines:
- •Elective coronary angiography due to symptoms suggestive for angina with a positive non-invasive ischemia assessment of ≥10% of left ventricle.
- •Non ST-elevation acute coronary syndrome with a GRACE score>110
排除标准
- •Patients on dialysis or those planned for dialysis in the next 3 months.
- •Patients with ST-elevation myocardial infarction
- •No symptoms or signs of heart failure
- •Treatment with IV diuretics during the 48 hours prior to enrolment
- •Patients with acute renal failure (Creatinine raise of at least 0.3mg/dl from )baseline
- •Patients post coronary artery bypass surgery
结局指标
主要结局
Changes in glomerular filtration rate following coronary angiography or intervention
时间窗: 24 and 48 hours post procedure
Significant changes are defined as a reduction ≥25% in glomerular filtration rate
次要结局
未报告次要终点
研究者
研究点 (1)
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