Concentrated Growth Factors in Regenerative Therapy in Furcation Involvements in Humans

Not Applicable

• Conditions: Periodontal Regeneration; Concentrated Growth Factors; Furcation Defects

• Registration Number: NCT03180658
• Lead Sponsor: Jing Qiao

Brief Summary

Objective: To compare the effect of guided tissue regeneration (GTR) + concentrated growth factors (CGF) + bone graft and CGF + bone graft in the treat of II° furcations of human mandibular molars. Methods: At least thirty II°furcation involvements in mandibular molars will be included and randomly divided into two groups. The experimental group will accept GTR + CGF + bone graft therapy, and the control group will accept CGF + bone graft therapy. The clinical examination and cone beam computed tomography (CBCT) will be performed at baseline and 1 year post-surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-05-01
• Study First Submitted: 2017-05-29
• Status Verified: 2017-06
• Study First Submitted QC: 2017-06-07
• Last Update Submitted: 2017-06-07
• Study First Posted: 2017-06-08
• Last Update Posted: 2017-06-08
• Primary Completion: 2020-05-01
• Study Completion: 2020-07-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• II° furcation involvements in mandibular molars
• after periodontal therapy.

Exclusion Criteria

• not healthy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
clinical measurement	1 year	Probing depth
clinical parameter	1 year	clinical attachment loss

Secondary Outcome Measures

Name	Time	Method
radiographic parameter	1 year	cone beam computerized tomographic scanning

Trial Locations

Locations (1)

Peking university School and Hospital of Stomatology; 🇨🇳 Beijing, Beijing, China