NCT04957823已完成不适用
Serum Irisin Level & FDNC5 Genetic Polymorphism Can Predict the Presence &Severity of Coronary Artery Disease in Patients With Type II DM?
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Irisin level
研究概览
简要总结
This is an observertional study aimed at Study the association between the level of irisin expression and (Fibronectin Type III Domain Containing 5 (FDNC5) gene polymorphism and the presence and severity of coronary artery disease in patients with Type II DM.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •This study will include type II diabetic patients aged between 18 and 45 years old
排除标准
- •Recent acute myocardial infarction.
- •patients with Heart Failure
- •Active infection
- •End stage renal failure (GFR < 30 ml/min) or on dialysis
- •Liver cell failure
- •Athletes or having heavy muscular exercise in the previous 3 days
结局指标
主要结局
Irisin level
时间窗: 6 months
detect the serum level of irisin hormone by ELIZA in nanogram/decilitre(ng/dl)
FNDC5 Genotyping
时间窗: 6 months
whether homogenetic or heterogenetic
次要结局
未报告次要终点
研究者
Amera Morad Foad
clinical professor
Sohag University
研究点 (1)
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