MedPath

The effect of low dose aspirin on platelet inhibition in patients with rheumatoid arthritis

Phase 1
Conditions
Condition 1: Rheumatoid arthritis. Condition 2: Rheumatoid arthritis.
Rheumatoid arthritis, unspecified
Registration Number
IRCT201707293812N6
Lead Sponsor
Connective Tissue research Center- Tabriz University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
45
Inclusion Criteria

Patients with rheumatoid arthritis who have been diagnosed with EULAR 2010 ACR criteria and have been ill for 6 months

Exclusion criteria:
Includes recent use of aspirin and anti-coagulant drugs, history of aspirin allergy, renal failure (creatinine above 8.1 mg / dL), thrombotic cytopenia, pregnancy, gastric ulcer and gastrointestinal bleeding. Patients with maternal and metabolic disorders are also among the exclusion criteria.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Platelet aggregation. Timepoint: One week. Method of measurement: Elisa.
Secondary Outcome Measures
NameTimeMethod
TXA2. Timepoint: one weak. Method of measurement: Elisa.;TX-A2. Timepoint: One week. Method of measurement: Elisa.
© Copyright 2025. All Rights Reserved by MedPath