Optimization of diagnosis and treatment plan for idiopathic membranous nephropathy in the integrative medicine
- Conditions
- Idiopathic Membranous Nephropathy
- Registration Number
- ITMCTR2200006126
- Lead Sponsor
- Shanxi Hospital of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
( 1 ) Patients with idiopathic membranous nephropathy ( IMN ) nephrotic syndrome confirmed by renal biopsy and clinical examination were pathologically divided into stages I to II ;
( 2 ) Age in 18-75 years old, gender, ethnic limit ;
( 3 ) signing informed consent ;
( 4 ) TCM syndromes are qi deficiency and blood stasis or damp heat and blood stasis ;
( 4 ) 24-hour urinary protein excretion > 3.5g / 24h
( 5 ) Serum creatinine = 133umol / L or endogenous creatinine clearance rate 60ml / min / 1.73m2 was included in the study.
( 1 ) Pregnancy or lactation patients ;
( 2 ) Complicated with severe primary diseases such as decompensated cirrhosis, active malignant tumor or hematopoietic system ;
( 3 ) Those with acute myocardial infarction, cerebral infarction or cerebral hemorrhage in the first three months were included ;
( 4 ) Severe arrhythmia, severe heart failure, NYHA class III or above ;
( 5 ) Patients with severe infectious diseases when included ;
( 6 ) Patients with clear thrombosis were included ;
( 7 ) During the treatment period, the patients with natural loss or loss of follow-up, poor compliance and discontinued or not taking medicine, there are serious adverse events, serious other patients with onset or deterioration.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method plasma albumin;24 hours urinary protein excretion;
- Secondary Outcome Measures
Name Time Method blood total cholesterol;serum creatinine;blood urea nitrogen;triglyceride;low density lipoprotein;urine routine;high density lipoprotein;