Exploring the Optimal Diagnosis and Treatment Strategy of Traditional Chinese Medicine Preparation Sangqi Qingxuan Ointment For Prevention and Treatment of Prehypertension and Grade 1 Hypertension:Based on the Regulation of Autonomic Nerve Functio
- Conditions
- hypertension
- Registration Number
- ITMCTR2200006668
- Lead Sponsor
- China-Japan Friendship Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
1. Understand the process of this trial, participate voluntarily and sign the informed consent
2. Meet the diagnostic criteria for primary hypertension grade 1 or prehypertension
3. In line with the TCM dialectical diagnosis of Yin deficiency of liver and kidney and/or hyperactivity of liver Yang and mutual junction of phlegm and blood stasis
4. No combined use of any western antihypertensive drugs
5. Age between 18 and 70
1. Those who cannot cooperate
2. Patients with secondary hypertension
3. Abnormal liver function, ALT, AST is more than 2 times the upper limit of normal
4. Kidney damage, blood creatinine greater than 133mmol/L
5. Patients with severe chronic gastrointestinal diseases
6. Active myocarditis or pericarditis
7. Unstable angina within 2 weeks
8. Planned cardiac surgery
9. Patients with significant hematologic disorders
10. Allergic to the test drug
11. Psychiatric disorders, drug or other substance abuse
12. Stressful situations such as surgery and severe trauma
13. Lactating women and women who are pregnant or preparing for pregnancy in the near future
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method blood pressure;
- Secondary Outcome Measures
Name Time Method blood pressure variability;heart rate variabiity;