Utilizing MRI for Earlier Diagnosis of Rheumatoid Arthritis
- Conditions
- Rheumatoid Arthritis
- Registration Number
- NCT03841279
- Lead Sponsor
- Mayo Clinic
- Brief Summary
MRI has been shown to be helpful in identifying patients who present with undifferentiated inflammatory arthritis who will develop RA within a one year follow up period. The absence of other clinically apparent symptoms often causes delays in diagnosis of RA. The use of the MRI in conjunction with the physical examination has the potential to reduce diagnostic delay. Earlier diagnosis would allow for earlier treatment implementation for better patient outcomes.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 100
≥ 18 years old
Undifferentiated inflammatory arthritis suspected to be early RA (≥1 joint with synovitis and ≥1 other tender joint)
Symptom duration ≤1 year
Unwillingness or inability to return to Mayo Clinic Rochester for research follow-up visits
Current or previous use of DMARDS
Taking ≥10 mg of prednisone a day
Contraindications to contract enhanced MRI
History of another definite autoimmune or inflammatory rheumatic disease
History of psoriasis
History of inflammatory bowel disease
Unsuitably as deemed by the principal investigator
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Earlier Diagnosis of RA if MRI is utilized 1 year To determine if MRI is predictive of later development of RA in patients with undifferentiated inflammatory arthritis; patients with inflammatory arthritis who receive an MRI will have earlier initiation of treatment
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Mayo Clinic
🇺🇸Rochester, Minnesota, United States