The significance of intestinal edema in sepsis - SIES

niversitätsklinikum Schleswig-Holstein, Campus Kiel, Klinik für Anästhesiologie und Operative Intensivmedizin0 sites170 target enrollmentApril 1, 2016

Conditionssepsis, severe sepsis, septic shock, blood poisoning R65.0 R65.1 R57.2 Systemic Inflammatory Response Syndrome of infectious origin without organ failure Systemic Inflammatory Response Syndrome of infectious origin with organ failure Septic shock

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: sepsis, severe sepsis, septic shock, blood poisoning
Sponsor: niversitätsklinikum Schleswig-Holstein, Campus Kiel, Klinik für Anästhesiologie und Operative Intensivmedizin
Enrollment: 170
Status: Not yet recruiting
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

No summary available.

Registry

who.int

Start Date

April 1, 2016

End Date

TBD

Last Updated

last year

Study Type

Observational

Sex

All

Investigators

Sponsor

niversitätsklinikum Schleswig-Holstein, Campus Kiel, Klinik für Anästhesiologie und Operative Intensivmedizin

Eligibility Criteria

Inclusion Criteria

•Arm 1: septic patients, surgical. Detailed: patients treated in the intensive care unit for severe sepsis and main surgery; severe sepsis or septic shock since \= 36h; main surgery since \= 48h.
•Arm 2: septic patients, non surgical. Detailed: patients treated in the intensive care unit for severe sepsis; severe sepsis or septic shock since \= 36h.
•Arm 3: surgical patients. Non septic. Detailed: patients treated in the intensive care unit after planned main surgery since \= 36h; perioperative need for \= 3000ml of fluids.
•Arm 4: healthy subjects undergoing routine endoscopy. Detailed: ambulant patients; planned examination of the upper and lower intestinal tract by endoscopy.

Exclusion Criteria

•inflammatory bowel disease (active), chronic liver failure (Child\-Pugh\-Classification C) or HIV disease, identified portal hypertension, identified portal vein thrombosis, identified hepatosplenomegaly, immunosupression, bone marrow or hematopoietic stem cell transplantation within the last 12 month, pregnancy or lactation, enrollment in an interventional study (within the last 30 days), enrollment in this study before, best supportive care.