Chronic Suppurative Otitis Media Microbiology

Not yet recruiting

• Conditions: Cholesteatoma; Microbial Colonization; Otitis Media, Suppurative Chronic
• Interventions: Diagnostic Test: Microbiological culture

• Registration Number: NCT06424704
• Lead Sponsor: Selcuk University

Brief Summary

This study is planned to reveal the microbiological agents and drug sensitivities to these agents in patients diagnosed with chronic suppurative otitis media who complain of ear discharge.

Detailed Description

Patients with complaints of ear discharge and who were diagnosed with chronic suppurative otitis media will be included in the study. Patients will be divided into two groups: CSOM with cholesteatoma and CSOM without cholesteatoma. One hundred ten patients from each group will be included in the study. After a comprehensive medical history is taken for each patient, the patient's external auditory canal will be cleaned with sterile aspirators. A sterile culture will be taken from the discharge of the ear and sent to microbiology. With the data obtained from microbiological examination, pathogens will be classified as gram-positive, gram-negative, anaerobic, and fungal and examined according to monomicrobial and polymicrobial growth. Antibiotic susceptibility tests will be conducted to determine the effectiveness of antibiotics against the bacteria causing the infection.

Study Timeline

• Status Verified: 2024-05
• Study Start: 2024-05-15
• Study First Submitted: 2024-05-16
• Study First Submitted QC: 2024-05-16
• Last Update Submitted: 2024-05-16
• Study First Posted: 2024-05-22
• Last Update Posted: 2024-05-22
• Primary Completion: 2026-05
• Study Completion: 2026-05

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 110

Inclusion Criteria

1. Patients diagnosed with chronic suppurative otitis media
2. Patients over 18 years of age

Exclusion Criteria

1. Chronic nonsuppurative otitis media patients
2. Patients diagnosed with external ear canal/middle ear malignancy
3. Patients who take immunosuppressive drugs
4. Immunosuppressive patients
5. Patients who used antibiotics (topical-systemic) in the last week

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Chronic suppurative otitis media without cholesteatoma (CSOM)	Microbiological culture	The study included patients who applied to Selçuk University Faculty of Medicine Hospital, Department of Ear, Nose and Throat Diseases \& Head and Neck Surgery, with complaints of ear discharge and were diagnosed with chronic suppurative otitis media without cholesteatoma.
Chronic suppurative otitis media with cholesteatoma (Chole)	Microbiological culture	Patients who applied to Selçuk University Faculty of Medicine Hospital, Department of Ear, Nose and Throat Diseases \& Head and Neck Surgery with complaints of ear discharge and were diagnosed with chronic suppurative otitis media with cholesteatoma were included in the study.

Primary Outcome Measures

Name	Time	Method
Microbiology of chronic suppurative otitis media	2024-2026 (24 months)	Microbiology in patients diagnosed with chronic suppurative otitis media with and without cholesteatoma

Secondary Outcome Measures

Name	Time	Method
Antibiotic susceptibility in chronic suppurative otitis media	2024-2026 (24 months)	Investigation of antibiotic susceptibility and resistance in patients diagnosed with chronic suppurative otitis media with and without cholesteatoma.

Trial Locations

Locations (2)

Bulent ULUSOY; 🇹🇷 Konya, Selcuklu, Turkey

Selcuk University; 🇹🇷 Konya, Selcuklu, Turkey