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临床试验/NCT06424704
NCT06424704尚未招募不适用

Microbiology of Chronic Suppurative Otitis Media: Prospective Study

Selcuk University2 个研究点 分布在 1 个国家目标入组 110 人开始时间: 2024年5月15日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
110
试验地点
2
主要终点
Microbiology of chronic suppurative otitis media

研究概览

简要总结

This study is planned to reveal the microbiological agents and drug sensitivities to these agents in patients diagnosed with chronic suppurative otitis media who complain of ear discharge.

详细描述

Patients with complaints of ear discharge and who were diagnosed with chronic suppurative otitis media will be included in the study. Patients will be divided into two groups: CSOM with cholesteatoma and CSOM without cholesteatoma. One hundred ten patients from each group will be included in the study. After a comprehensive medical history is taken for each patient, the patient's external auditory canal will be cleaned with sterile aspirators. A sterile culture will be taken from the discharge of the ear and sent to microbiology. With the data obtained from microbiological examination, pathogens will be classified as gram-positive, gram-negative, anaerobic, and fungal and examined according to monomicrobial and polymicrobial growth. Antibiotic susceptibility tests will be conducted to determine the effectiveness of antibiotics against the bacteria causing the infection.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients diagnosed with chronic suppurative otitis media
  • Patients over 18 years of age

排除标准

  • Chronic nonsuppurative otitis media patients
  • Patients diagnosed with external ear canal/middle ear malignancy
  • Patients who take immunosuppressive drugs
  • Immunosuppressive patients
  • Patients who used antibiotics (topical-systemic) in the last week

结局指标

主要结局

Microbiology of chronic suppurative otitis media

时间窗: 2024-2026 (24 months)

Microbiology in patients diagnosed with chronic suppurative otitis media with and without cholesteatoma

次要结局

  • Antibiotic susceptibility in chronic suppurative otitis media(2024-2026 (24 months))

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Bulent Ulusoy

Selcuk University Faculty of Medicine

Selcuk University

研究点 (2)

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