The Effects of TAP Block on Postsurgical Pain After Minimally Invasive Partial Nephrectomy:

Not Applicable

Completed

• Conditions: Chronic Pain; Acute Pain
• Interventions: Procedure: intravenous Patient controlled analgesia; Procedure: Tap block; Drug: Morphine; Drug: Ropivacaine

• Registration Number: NCT02460640
• Lead Sponsor: Regina Elena Cancer Institute

Brief Summary

Single-center study in order to assess whether the tap block can make extremely beneficial in terms of reducing the acute and chronic pain as well as for use of opioids and side effects related to it in patients undergoing surgery to minimally invasive partial nephrectomy.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-05
• Study First Submitted: 2015-05-19
• Study First Submitted QC: 2015-06-01
• Study First Posted: 2015-06-02
• Primary Completion: 2017-08
• Study Completion: 2017-08
• Status Verified: 2018-01
• Last Update Submitted: 2018-01-31
• Last Update Posted: 2018-02-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 96

Inclusion Criteria

• asa score I,II,II
• patients scheduled for robot assisted partial nephrectomy

Exclusion Criteria

• previous abdominal surgery
• inability to provide informed consent
• allergy to the anesthetic drugs

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
No Tap Block	intravenous Patient controlled analgesia	the patients who not receive tap block but they will be as intervention intravenous Patient controlled analgesia
Tap Block	intravenous Patient controlled analgesia	the intervention will be tap block after induction of anesthesia with ropivacaine 0,5% 15ml and continuous patient-controlled analgesia with morphine
Tap Block	Tap block	the intervention will be tap block after induction of anesthesia with ropivacaine 0,5% 15ml and continuous patient-controlled analgesia with morphine
Tap Block	Morphine	the intervention will be tap block after induction of anesthesia with ropivacaine 0,5% 15ml and continuous patient-controlled analgesia with morphine
Tap Block	Ropivacaine	the intervention will be tap block after induction of anesthesia with ropivacaine 0,5% 15ml and continuous patient-controlled analgesia with morphine
No Tap Block	Morphine	the patients who not receive tap block but they will be as intervention intravenous Patient controlled analgesia

Primary Outcome Measures

Name	Time	Method
Morphine consuption 24 hr after surgery	24 hours	Cumulative morphine consuption (mg) 24 hr starting from the time of extubation.
Acute pain after surgery measured with Numerical Rating Scale	24 hours	patients were assessed for pain, according to Numerical Rating Scale (NRS; 0: no pain to 10: worst pain imaginable)

Trial Locations

Locations (1)

Regina Elena CI; 🇮🇹 Rome, Italy