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The effects of physical training, Aspirin, and Clopidogrel on the walking capacity of patients with stage II peripheral arterial disease

Conditions
Peripheral arterial disease, intermittent claudication
Registration Number
EUCTR2004-005041-35-DE
Lead Sponsor
niversity Hospital Basel, Dept. of Angiology
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
250
Inclusion Criteria

Established diagnosis of PAD
Treadmill tested initial claudication distance (ICD) between 50 and 400 meters
ICD variability during run-in phase less than 25%
History of intermittent claudication longer than 3 months
Stabilised treatment of concomitant diseases
Written informed consent
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Treatment with oral anticoagulants
Surgical vascular reconstruction or catheter based intervention within last 3 months
Age less than 45 years (m) and childbearing potential (f)
Buerger's disease
Peptic ulcer within the previous 6 months
History of GI or any other bleeding disorder within the previous 6 months
Consuming disease with life expectancy of less than 2 years

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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