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Efficacy Study on Quality of Life Criteria of a Digital Application on Any Cellphone (OnKO-Tips&Tricks) for Adolescents and Young Adults Diagnosed With Cancer

Not Applicable
Recruiting
Conditions
Cancer
Interventions
Other: OnKO-Tips&Tricks digital phone application
Registration Number
NCT05350631
Lead Sponsor
University Hospital, Strasbourg, France
Brief Summary

Approximately 2,200 cancers per year in France are diagnosed within the adolescents and young adults population (15-25 years old, AYA). The cancer plans and the INCA recommend support during and after cancer treatment, taking into account both medical and psycho-social specificities related to age (support care, school learning/training and professional integration, fertility preservation, therapeutic education, addictology, sexology...). In this context, AJA teams have been developed in which the Nurse Coordinators (IDEC) play a fundamental role. These Nurse Coordinators are available to young patients, their families and the professionals who accompany follow them in their therapeutic journey. Their main missions are to assess the specific needs of these young people and their loved ones, to inform, orient and participate in the coordination of their care by providing psychosocial and paramedical solutions to these young patients. The circular of 30/05/2016 on the coordinated regional organization of care for AJAs supports the development of connected health tools for AJAs. This population is adept to new technologies, social networks allowing them to continue to be informed and remain integrated to the outside world while helping them prepare for life after cancer.

In this context, our team initiated the development of a digital application compatible for any cellphone OnKO-Tips\&Tricks meeting these criteria of necessity with the company CAPCOD. We would want to move on to a validation stage by carrying out a national multicenter efficacy study in AJA mobile units by comparing two groups of patients: users/non-users of this digital tool on a main criterion of quality of life after using it for 6 months. As it should promote autonomy and integration into the care pathway as well as active participation in therapeutic education programs (TPE), these different items will be evaluated as secondary endpoints of our study

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
200
Inclusion Criteria
  • Patient age ≥ 15 years and ≤ 25 years
  • Diagnosed with solid or blood cancers less than 1 month old or patient with relapsed cancer more than 5 years after completion of initial treatment
  • Follow-up at one of the participating study centers
  • Informed and signed consent from the patient and, if the subject is a minor, from the holders of parental authority
  • Inclusion in the study at the latest at the time of initiation of chemotherapy or radiotherapy
  • Patient agrees to 12-month post-inclusion follow-up
  • Patient agreeing to complete all study questionnaires
  • Patient with a cellphone capable of downloading the app (developed for all types of cellphones)
  • Affiliated to a social health insurance plan
Exclusion Criteria
  • Patient deprived of liberty by a judicial or administrative decision
  • Patient with protected person status
  • Patient who does not understand, speak or write French
  • Patient unable to understand the follow-up protocol according to the investigating physician or the IDEC of the AJA unit
  • Patient with a scheduled hospitalization of at least 5 weeks during study participation

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
ExperimentalOnKO-Tips&Tricks digital phone applicationusing a digital tool in addition to follow-ups by consultations, phone contact and PTE workshop with the AJA mobile team centralized by the IDEC
Primary Outcome Measures
NameTimeMethod
Evaluate the efficacy of the OnKO-Tips&Tricks digital phone application on the psychosocial dimension of patients' quality of life6 months of inclusion

Assessed using a psychosocial health score obtained by the Pediatric Quality of Life Inventory™ Version 4.0 Generic Core Scales questionnaire.

The PedsQL 4.0 Generic Core Scale contains 23 items that measures physical (eight items), emotional (five items), social (five items), and school (five items) functions. The Scale comprises parallel patient self-report and parent proxy-report formats. The items are reverse-scored and trans- formed to a 0-100 scale according to the instructions, and higher scores indicate a better HRQOL.

Secondary Outcome Measures
NameTimeMethod
Evaluate the impact on each patient's participation in a therapeutic education program (TPE)through study completion, an average of 1 year and 6 months

Rate of patients in the experimental and control groups who will participate in the proposed FTE program

Evaluate the efficacy of the OnKO-Tips&Tricks digital phone application on the psycho-social dimension of patients' quality of life3 months and 12 months of inclusion

Assessed using a psychosocial health score obtained from the Pediatric Quality of Life Inventory™ Version 4.0 Generic Core Scales questionnaire.

The PedsQL 4.0 Generic Core Scale contains 23 items that measures physical (eight items), emotional (five items), social (five items), and school (five items) functions. The Scale comprises parallel patient self-report and parent proxy-report formats. The items are reverse-scored and trans- formed to a 0-100 scale according to the instructions, and higher scores indicate a better HRQOL.

Assess patient satisfaction with the use of the OnKO-Tips&Tricks digital phone application using the MAUQ questionnaire6 and 12 months

Evaluated using the mHealth app usability questionnaire (MAUQ questionnaire).

Evaluate the efficacy of the OnKO-Tips&Tricks digital phone application on patients' overall and physical quality of life3 months, 6 months and 12 months of inclusion

Assessed using total Quality of Life and physical health subscore scores obtained from the Pediatric Quality of Life Inventory™ Version 4.0 Generic Core Scales questionnaire.

The PedsQL 4.0 Generic Core Scale contains 23 items that measures physical (eight items), emotional (five items), social (five items), and school (five items) functions. The Scale comprises parallel patient self-report and parent proxy-report formats. The items are reverse-scored and trans- formed to a 0-100 scale according to the instructions, and higher scores indicate a better HRQOL.

Evaluate the efficacy of the OnKO-Tips&Tricks digital phone application throughout the patient's care pathway3 months, 6 months and 12 months of inclusion

assessed by the number of consultations, medical and paramedical, the number of outpatient management, the number of unscheduled hospitalizations, the number of listed side effects, and the number of phone contacts (text, calls) and emails initiated by the patient towards the IDEC.

Evaluate the adherence to the application in the experimental groupPer week and per month through study completion, an average of 1 year and 6 months

Evaluated by collecting the number of uses of each feature

Evaluate the efficacy of the OnKO-Tips&Tricks digital phone application on the quality of life of patients according to cancer pathology6 months of inclusion

Comparative analysis of quality of life collection using the Pediatric Quality of Life Inventory™ Version 4.0 Generic Core Scales questionnaire taking into account the type of cancers: solid vs. blood cancer The PedsQL 4.0 Generic Core Scale contains 23 items that measures physical (eight items), emotional (five items), social (five items), and school (five items) functions. The Scale comprises parallel patient self-report and parent proxy-report formats. The items are reverse-scored and trans- formed to a 0-100 scale according to the instructions, and higher scores indicate a better HRQOL.

Trial Locations

Locations (10)

Institut d'Hématologie et d'Oncologie Pédiatrique

🇫🇷

Lyon, France

CHU Rennes Hôpital Sud

🇫🇷

Rennes, France

Hôpital enfant-adolescent

🇫🇷

Nantes, France

CHU de Nice Hôpital Archet 2

🇫🇷

Nice, France

Institut de Cancerologie Strasbourg Europe

🇫🇷

Strasbourg, France

Assistance Publique - Hôpitaux de Marseille

🇫🇷

Marseille, France

CHU Reims - Hôpital Maison Blanche

🇫🇷

Reims, France

Institut de Cancérologie de l'Ouest

🇫🇷

Saint-Herblain, France

Institut Gustave Roussy

🇫🇷

Villejuif, France

Hôpitaux Universitaires de Strasbourg

🇫🇷

Strasbourg, France

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