The effect of two different doses of mannitol on the reduction of creatine phosphokinase in brain death patients
Phase 2
- Conditions
- Brain death.Brain deathG93.82
- Registration Number
- IRCT20200825048515N67
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Confirmation of the patient's brain death
Having the age of 16 to 55 years
Confirmation of the patient's eligibility for kidney donation by the relevant team
The presence of creatine phosphokinase greater than or equal to 5000 units per liter in the patient's initial test
Consent of the patient's companions to perform the transplant and participate in the study
Exclusion Criteria
Having a pacemaker
Heart failure
Sepsis
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Creatine phosphokinase. Timepoint: 8 hours after receiving each dose of mannitol. Method of measurement: Blood test.;Creatinine. Timepoint: 8 hours after receiving each dose of mannitol. Method of measurement: Blood test.;Sodium. Timepoint: 8 hours after receiving each dose of mannitol. Method of measurement: Blood test.;Potassium. Timepoint: 8 hours after receiving each dose of mannitol. Method of measurement: Blood test.
- Secondary Outcome Measures
Name Time Method Blood pressure. Timepoint: 2 hours after receiving each dose of mannitol. Method of measurement: Sphygmomanometer.;Heart beat. Timepoint: 2 hours after receiving each dose of mannitol. Method of measurement: Pulse oximeter.