A study of the effect of nicergoline for dysphagia in patients with aspiration pneumonia - The effect of nicergoline in dysphagia

Significant elevations of serum substance P were obtained by both medications (nicergoline or imidapril) after 4 weeks of treatment. -Patients whose dysphagia was improved showed significantly increased serum levels of substance P. -There was no statistically significant difference in the overall proportion of patients who showed improvements in dysphagia and pneumonia recurrence with imidapril or nicergoline treatment. -Nicergoline, but not imidapril, seemed to be more effective at improving dysphagia and elevating serum substance P in patients with dementia.