To compare the effect of two anticonvulsant drugs levetiracetam and phenobarbitone in neonates with seizures.
Phase 3
- Conditions
- Health Condition 1: G89-G99- Other disorders of the nervous system
- Registration Number
- CTRI/2022/09/045658
- Lead Sponsor
- Sarojini Naidu Children Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All neonates with clinical seizures not controlled after correction of hypoglycemia and hypocalcemia
Exclusion Criteria
Neonates already on anticonvulsant therapy
neonates with unstable vitals
neonates with major congenital malformations
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method cessation of seizures within 48 hours of administration of first or second loading dose of the drug [ levetiracetam Vs Phenobarbitone]Timepoint: 48 hours
- Secondary Outcome Measures
Name Time Method Adverse immediate effects within 3 hours <br/ ><br>The percentage of neonates who failed treatment with either levetiracetam or phenobarbitoneTimepoint: 3 hours