Effect of giving ketamine nebulization before surgery to reduce occurance of throat pain due to tracheal intubation after surgery
Phase 2
- Conditions
- Health Condition 1: H661- Chronic tubotympanic suppurative otitis media
- Registration Number
- CTRI/2020/08/027327
- Lead Sponsor
- SSG HospitalVadodara
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1) Patients posted for elective surgery under general anesthesia requiring endotracheal intubation in supine position with surgery duration of 1-3 hours.
2) Age: 18-60 years
3) Gender: Either gender.
4) ASA I & II
Exclusion Criteria
1-Patientâ??s refusal.
2-History of prior sore throat
3-Patients using steroids or NSAIDS
4-Patients with COPD, asthma
5-Patient with difficult airway.
6-Known allergy to study drug.
7-Surgery involving oral cavity, nasopharynx, neck region and surgeries with throat pack.
8-Pregnant patients.
9-Patients with >1 attempt of intubation
10-Presence of excessive bucking at time of extubation.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate efficacy of nebulized ketamine in reducing incidence and severity post-operative sore throat in adult patients undergoing general anesthesiaTimepoint: The incidence and severity of sore throat will be recorded at 2,4,6, 12 and 24 hours post operatively, measured on 4 points scale 0-3
- Secondary Outcome Measures
Name Time Method 1-to observe for side effects like cough,nausea,vomiting,hallucination <br/ ><br>2-to observe relation between gender and duration of surgery to incidence of post operative sore throat <br/ ><br>3- to compare hemodynamics between both groupsTimepoint: pre nebulisation,5 mins post nebulisation,at time of induction,10 mins post-induction,post-extubation. <br/ ><br>and 0,2,4,6,12,24 hourly