Lifestyle and Dietary Pattern in Relation to Precursor Lesions of Colorectal Cancer and Cardiometabolic Diseases Among High-risk Populations in Lanxi, China
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 25,000
- 试验地点
- 2
- 主要终点
- Numbers of participants with polyps
研究概览
简要总结
The association between lifestyle and dietary patterns with precursor lesions of colorectal cancer and cardiometabolic diseases is still unclear. This study is conducted in Jinhua, a city with a high prevalence of colorectal cancer in China, to assess the relationship between lifestyle and dietary factors with precursor lesions of colorectal cancer and cardiometabolic diseases.
详细描述
Investigations of lifestyle and dietary factors in relation to precursor lesions of colorectal cancer and cardiometabolic diseases are limited in China. The investigators aim to collect the basic characteristics of participants at baseline, including sex, age, smoking, exercise, marriage, education level, dietary factors and so on, to assess the associations between lifestyle and dietary factors with precursor lesions of colorectal cancer and cardiometabolic diseases. This large cohort - the Lanxi Pre-colorectal Cancer Cohort (LP3C) also included several subcohorts consisting of patients with CVD, diabetes, hypertension, metabolic syndrome, obese/overweight or fatty liver disease. Results from this study will be valuable for colorectal cancer and cardiometabolic disease prevention in China.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 45 Years 至 74 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Subject aged ≥45 and ≤74 years old
- •Subject has complete data on diet and follow-up time
排除标准
- •Colorectal cancer
- •Severe intestines problems
结局指标
主要结局
Numbers of participants with polyps
时间窗: From entry into the study (baseline:2018-2022) until 2028
All polyps
次要结局
- Numbers of participants with different subtypes of polyps(From entry into the study (baseline:2018-2022) until 2028)
- Numbers of participants with cardiometabolic diseases(From entry into the study (baseline:2018-2022) until 2028)
研究者
Jingjing Jiao
Associate Professor
Zhejiang University